Application Notes: LC
Chiral Columns for Oligonucleotides Analysis (Nov 2023)
Accurate purity assessment of oligonucleotide mixtures can be challenging due to their complexity. Daicel offers several solutions that provide unique selectivity.
Determination of Adenine and Guanine Nucleotides
The measurement of adenosine nucleotides represents important diagnostic measures concerning metabolic standing for the determination of various pathological states.
Separation of Fat-Soluble Vitamin K Congeners
The coagulation benefits of vitamin K1 are well known, however, the other congeners of the vitamin series are not as common (K2, K3, and K4), but equally contribute to a healthy disposition.
Poisoned by Plastic: Analysis of BPA (Nov 2023)
Plasticizers added to water bottles to add stability to the bottles can be unknowingly extracted in drinks leading to possible endocrine interactions.
Legumes – Blessing and Curse (Nov 2023)
Discover how the HC-75 series uses a ligand exchange mechanism in order to interact more or less strongly with the analytes of interest.
Oligonucleotide Purification by Reversed-Phase Ion Pairing (Nov 2023)
Hamilton's PRP-C18 column gave good separation with various gradient profiles and under various particle sizes. The excellent loading capacity of the column make this stationary phase desirable.
Separating 12 Nucleosides on Hamilton Column
Modified nucleosides, either natural or synthetic, often provide RNA with distinctive properties useful in diagnostics or therapeutics.
Cannabis Potency by LC-DAD
This demonstrates how to perform cannabis potency analysis using HPLC-UV, displaying the advantages of this technique for analyzing acidic cannabinoids.
Comparing HPLC flow rate measurement techniques
Accurate determination of flow rate is an increasingly favoured method of assessing or validating the performance of a pump serving a liquid chromatography system.
Separation of Fat-Soluble Vitamin K Congeners in Under 6 Minutes
A fast, simple method using the PRP-C18 column allows for simple, efficient identification of the natural and synthetic compounds of vitamin K (K2, K3, and K4).