Market Profile: UHPLC
Market Profile: UHPLC
Ultrahigh-performance liquid chromatography (UHPLC) systems are designed to take full advantage of smaller particles (sub 2 μm), which yield higher resolution and increased sensitivity. Because of increased back pressure, UHPLC systems employ high-performance pumps that deliver 15 000 psi (1,000 bar) or more of pressure. Some systems solve the back-pressure issue by elevating temperatures using a column oven, which lower the viscosity of the mobile phase, allowing it to move faster through the column. UHPLC systems have been shown to provide analysis times of less than 1 min and up to 40 times faster than conventional HPLC systems.
New HPLC, MS, and CDS Products from 2024–2025: A Brief Review
June 5th 2025This review highlights the high performance liquid chromatography (HPLC), mass spectrometry (MS), chromatography data systems (CDS), and related products that were introduced from 2024 to 2025, summarizing the technical specifications of each product and highlighting significant user benefits.
Identifying Chinese Medicine Components Using UHPLC Techniques
June 2nd 2025A type of traditional Chinese medicine that is believed to address depression symptoms, scientists recently studied the medicine’s components of the Xiaoyao Pill (XYP) to measure its effectiveness and identify its components.
Salting-Out Coupled with UHPLC-MS/MS for Tryptophan Metabolite and Bile Acid Profiling
May 29th 2025In a new study, researchers explored quantifying bile acids and tryptophan metabolites in human serum samples was created using ultrahigh-performance liquid chromatography coupled with tandem mass spectrometry (UHPLC–MS/MS).
