About LCGC International
Founded in 1983, LCGC International is the leading provider of digital and print content to the separation science market, enhancing the productivity, efficiency, and the overall value of separation techniques globally. With our commitment to editorial excellence, we have pioneered innovation across a broad portfolio of digital and print platforms.
Through our monthly print publication, website, newsletters, ebooks, webcasts, interviews, and special issues, which provide unbiased peer-reviewed articles, trusted troubleshooting advice, and best-practice applications solutions, LCGC International covers all key growth areas in the field of separation science. Laboratory-based analytical chemists and influential chromatographers can improve productivity and enhance their proficiency through LCGC International’s practical information, giving them a competitive advantage for the real-world challenges they face.
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AI and GenAI Applications to Help Optimize Purification and Yield of Antibodies From Plasma
October 31st 2024Deriving antibodies from plasma products involves several steps, typically starting from the collection of plasma and ending with the purification of the desired antibodies. These are: plasma collection; plasma pooling; fractionation; antibody purification; concentration and formulation; quality control; and packaging and storage. This process results in a purified antibody product that can be used for therapeutic purposes, diagnostic tests, or research. Each step is critical to ensure the safety, efficacy, and quality of the final product. Applications of AI/GenAI in many of these steps can significantly help in the optimization of purification and yield of the desired antibodies. Some specific use-cases are: selecting and optimizing plasma units for optimized plasma pooling; GenAI solution for enterprise search on internal knowledge portal; analysing and optimizing production batch profitability, inventory, yields; monitoring production batch key performance indicators for outlier identification; monitoring production equipment to predict maintenance events; and reducing quality control laboratory testing turnaround time.
