Application Notes: General
Application Note: Native Online HIC–MS Analysis of mAbs
Charge variants of 28 mAbs were analyzed under MS-compatible conditions using YMC’s BioPro IEX SF column. Each mAb of different pI was separated from its variants
Charge Variant Analysis of 28 mAbs
Leuprorelin Analysis Using YMC-Triart Bio C18
In reference to the Japanese Pharmacopeia, YMC-Triart Bio C18 was used to analyze the peptide leuprorelin (GnRH analogue) and separate it from its degradation products.
Analysis of Bevacizumab by SEC–MALLS
In this application note, YMC’s dedicated SEC column for antibodies, YMC-SEC MAB, has been used to develop a method for bevacizumab using MALLS detection.
Application Note: Native Online SCX-MS Analysis of mAbs
LC–HRMS Analysis of the ASO Mipomersen
Mipomersen was analyzed by LC–HRMS using a biocompatible YMC-Triart C8 metal-free column ensuring symmetric peaks, high sensitivity, and no carryover effects.
SEC Separation of ADC Brentuximab Vedotin
The antibody-drug conjugate was separated from its aggregates and fragments in only one run using a YMC-SEC MAB column and varying mobile phases.
Application Note: Native Online HIC–MS of Cys-linked ADCs
In this application note, the DAR of the SigmaMAb ADC-mimic was determined using YMC’s BioPro HIC BF column and a nanospray ionization mass spectrometer.
PTR-TOF Mobile Air Quality Monitoring
IONICON real-time VOC analyzers are frequently deployed in mobile laboratories, contributing to public safety, tracking air pollution where and when it matters.
How to Know if a Gas Generator is the Right Choice for Your Lab
Supplying Nitrogen for LC-MS with an In-House Gas Generator Improves Laboratory Safety, Increases Efficiency, and Reduces Cost
A Sustainable Approach to the Supply of Nitrogen
A Q&A - The Ins and Outs of Starting a Cannabis Testing Lab
Effect of Purging a Sealed and Desiccated FTIR Spectrometer Sample Compartment
Hydrogen Safety Questions - Safe Alternative to Gas Cylinders
Get your free printed GPC Troubleshooting and Columns & Standard posters
µPAC Generation 2: nanoLC Column Performance
The unique design of the 50 cm μPAC™ GEN2 nanoLC column provides superior performance over state-of-the-art packed bed columns, achieving peak capacities of over 1000.
Chiral Stationary Phase Comparison for the Enantioseparations of 20 Agrochemical Compounds
Practical Considerations for High-Throughput Chiral Screening in HPLC and SFC with 3- and Sub-2-µm Particle-Packed Columns
Gradient HPLC-UV Method for Cannabinoid Profiling
LC–MS Screening for Mycotoxins in Beer Grains and Beer
Here we present a mycotoxin screening method for beer grain and beer samples utilizing a HALO PFP column, which enables high sensitivity, high resolution, and high-speed separations for this analysis.
Reverse Engineering the Aroma of Plant-Based Meat Substitutes
The use of headspace sorptive extraction with GC×GC–TOF-MS to compare the volatile profiles of ground meat and plant-based substitutes.
Differentiating Four THC Stereoisomers Formed from Δ9-THC Degradation
Discover a reliable and robust HPLC method to separate Δ10-THC and Δ6a,10a-THC isomers produced from Δ9-THC degradation using a chiral HPLC stationary phase.
The Chiral Separation of Remdesivir and Several of Its Key-Starting Materials
See chiral separations for anti-viral COVID-19 treatment Remdesivir and its phosphoramidite and nucleoside key-starting materials, on Daicel chiral and achiral columns.
Analysis of VOCs Using EPA 524.3
In EPA 524.3, environmental labs are allowed to modify purge and trap/GC-MS conditions for drinking water samples. CDS 7000 series product meets and exceeds the requirements.
Analysis of VOCs Using EPA 524.4 v2
In EPA 524.4, nitrogen replaced helium in purging VOCs from drinking water samples. CDS 7000 concentrator with a 7450 autosampler meets and exceeds the requirements.
Quantitative Thermal Desorption Sample Split
This application note demonstrates the quantitative sample split capability of 7550S thermal desorber for a group of VOCs with boiling point up to 218 °C.
HEM extraction using the Empore EZ-Trace
This application note demonstrates the ability of the Empore EZ-Trace SPE Workstation to effectively extract HEM from water samples under EPA Method 1664.
Quantitative Analysis of Residual Monomer
This application note demonstrates quantitative analysis of monomer contamination in a polymer by TD-GC-MS method in a CDS Pyroprobe.
EGA and Multi-Step Pyrolysis of Bakelite
This application note investigates the thermal decomposition of Bakelite phenol-formaldehyde resin using EGA and multi-step pyrolysis GC-MS.