Application Notes: General
Legacy and Emerging PFAS
A robust and reliable solution for monitoring for 40 PFAS compounds including replacements like HFPO-DA, and short-chain analytes.
Optimizing LC and LC–MS methods with better LC columns
Using fast, efficient HALO® Fused-Core® technology columns and manipulating selectivity quickly develops methods for fast, high-efficiency LC and LC–MS separations.
LC–MS Separation SAMHSA 5 Panel
This application demonstrates HALO® Biphenyl is an ideal choice for high throughput analysis of drug panels, in which isobaric species separation is needed.
Comparative LC Separation of NSAIDs
The separation of non-steroidal anti-inflammatory drugs 60% less time, with better resolution than a typical HPLC column packed with fully porous particles, is demonstrated.
A Commitment to Innovation, Quality, and Experience
This document demonstrates how AMT improves the presentation of the sample to the detector using our Fused-Core® particle design and quality manufacturing.
LC Separation of Ten Phenolic Acids
This application note demonstrates the separation of ten phenolic acids with excellent speed and resolution due to the HALO RP-Amide column.
Surmounting the Challenges of Bispecific Antibody Characterization
LC/MS of Intact Adeno-Associated Virus Capsid Proteins for Rapid Confirmation of Product Identity
Robust, Reliable, Recombinant Protein A Monolith Column for Antibody Titer Determination
Analysis of Camelid Single-Domain Antibodies Using Agilent AdvanceBio SEC 120 Å 1.9 μm and AdvanceBio HIC Columns
App Note: Characterization of Viral Vector Particles Using the Agilent 6545XT AdvanceBio LC/Q-TOF
Purification of Single-Stranded RNA Oligonucleotides Using High-performance Liquid Chromatography
Direct Analysis of PFAS in Multiple Samples
This application note demonstrates analysis at low levels (ng/L) in a wide variety of matrices for EPA 8327 method validation.
PFAS Determination in Drinking Water
This application note describes an efficient and reliable method to meet U.S. EPA Method 537.1.
Advances in UHPLC/HPLC 2021
High-Resolution Analysis of Monoclonal Antibodies Using the Cation Exchange Column BioPro IEX SF
This application note investigates the use of YMC BioPro SF for high-resolution charge variant analysis of four therapeutic mAb products.
Method Development of IEX mAb Separations Using YMC BioPro IEX Columns and Dial-a-Mix v2
The dial-a-mix method with a quaternary pump HPLC quickly screens different method conditions when developing ion-exchange methods for charge variant analysis of mAbs.
Use of YMC-Triart PEEK-Lined Columns for Improved Peak Shape of Coordination Compounds
This application note describes the benefits of using YMC-Triart PEEK-lined columns for separations involving coordination compounds.
HPLC Separation of 11 Cannabinoids on YMC-Triart C18
This application note investigates using YMC-Triart C18 for analysis of 11 common cannabinoid compounds.
Next Generation RP Phase for Enhanced Insulin Purification
This application note details real-life client data obtained for insulin purification and manufacturing using YMC’s new YMC-Triart Prep Bio200 C8 material.
YMC SEC Columns and Light Scattering Detection
This application note details the use of light scattering detection coupled with SEC analysis for characterization of proteins and antibodies.
App Note: Extraction of Pesticides from Black Tea
Automated liquid extraction of pesticides from tea that eliminates the use of salts and sorbents. In less than 15 min, get filtered sample that is ready for analysis.
Compliance-Ready Mass Spectrometry for Bio/Pharmaceutical Analysis and Development
Monitoring Volatile Organic Compounds in Beer Production
Here we describe a system to extract and concentrate VOCs from a beer sample and deliver them to a GC–MS instrument for separation, identification, and quantification.
Characterization of Hop Aroma Using GC–MS
An efficient method of NDMA and NDEA analysis using a single-step extraction and direct injection into a GC–MS instrument for separation and quantification is described.
Analysis of Butylated Hydroxytoluene in Food
This application note will demonstrate a fast and easy analytical technique to determine the amount of BHT in foods using Headspace GC–MS without sample preparation.
Coffee Characterization Using GC–MS and Olfactory Port
This app note presents a system for characterizing finished coffee aroma while simultaneously performing chemical analysis on a mass spectrometer.
The Determination of Nitrosamines in Beer
Evaluation of Aromas in Grape Products
In this application note, we present an analytical approach for the fast and simple analysis of aromatic compounds in complex food matrices using HS-SPME–GC–MS. Text
Determination of Furan in Food by GC–MS
Demonstrates a rapid method for the identification and quantification of furan in food samples, using gas chromatography with headspace sampling and mass spectrometry.