Application Notes: General
Convenient and Reliable Analysis of Antibody Drug Conjugates
Automated Workflow for Monoclonal Antibody N-Linked Glycan Analysis
Resolution and Speed in the Separation of Glycans
Biopharma LC Column Selector
Monitoring Product-Related mAb Fragments
High-throughput Analysis of DNA Modifying Enzymes by an Agilent RapidFire 360 System
Evaluation of SEC Columns for Analysis of ADC Aggregates and Fragments
N-Glycan Analysis of Biotherapeutic Glycoproteins using AdvanceBio Gly-X InstantPC Sample Preparation and LC/FLD/MS
AdvanceBio Sialic Acid Profiling and Quantitation Kit
Rapid Assessment of Biosimilarity of Therapeutic Proteins Using ZipChip
Characterization of mAb glycoforms on FcγRIIIA-ligand
This application note demonstrates the scalability from analytical to semi-preparative mode while maintaining similar resolution between the two different capacity columns.
FcR Affinity Chromatography for Upstream Development
A new approach to assess glycan profiles during cell line screening.
Orthogonal Analysis of mAb ADCC Activity
mAb Characterization by FcR Affinity Chromatography and HILIC–MS
This two-step workflow allows for the rapid screening of N-linked glycans for upstream and downstream mAb production.
Glycan Pattern and ADCC Activity Analysis v2
This application note demonstrates that FcγRIIIA affinity chromatography allows fast assessment of biologic activity and glycoform pattern of antibodies.
LC Column Chemistries for Full Coverage of PFAS Analyte Ranges v2
A wide variety of LC column chemistries were evaluated to demonstrate new chromatographic approaches to complex PFAS analyte lists.
Strata® GCB for PFAS Extraction and Clean-Up v2
Phenomenex announces a new graphitized carbob black (GCB) SPE tube for DOD QSM 5.3 compliant PFAS analysis.
EPA Method 537.1 - PFAS in Drinking Water v2
Strata-SDB-L and Luna Omega 1.6 µm PS C18 demonstrate excellent precision and recovery in EPA Method 537.1 for the analysis of PFAS in drinking water.
Perfluoroalkyl Substances (PFAS) Testing Guide v2
Application guide to PFAS analysis in environmental and food samples, from sample preparation to LC–MS/MS analysis, featuring both validated and exploratory methods.
PFAS Analysis Using a pH-Variable LC Mobile-Phase Gradient v2
A novel LC approach to manipulate the chromatography of closely related PFAS analytes to separate co-eluties and avoid matrix interferences.
California PFAS Panel Analysis in Drinking and Wastewater v2
Validation of a water and wastewater method for the California PFAS panel using SPE (WAX/GCB) preparation and LC–MS/MS analysis with a variable pH LC mobile phase
Fast and Economical PFAS Extraction Using Strata PFAS v2
Strata PFAS (WAX and GCB combined in a single SPE tube) compliant with DOD QSM 5.1, but more accurate, precise, and economical than dual tube or dispersed GCB solutions.
PFAS in Food using QuEChERS, SPE, and LC–MS/MS v2
A QuEChERs + SPE sample preparation technique coupled with LC–MS/MS is shown to provide sub-ppb analysis of PFAS in dairy and fish samples.
EPA Method 533: PFAS in Drinking Water v2
In a commercial laboratory setting, Strata-X-AW and Gemini 3 µm C18 show excellent precision and recovery in EPA Method 533 for the analysis of PFAS in drinking water.
Optimizing Control of Pump-Related Processes
This white paper will illustrate how integrated pump controllers optimize pump performance by automatically controlling flow or pressure.
Electrochemical Reduction of Biopharmaceuticals
With a new electrochemical cell, complete reduction of inter- and intra-disulfide bonds in mAbs is achieved with superior sequence coverage.
An Introduction to Low-Pressure GC-MS (LPGC-MS)
LPGC–MS is a technique that uses the MS vacuum system, along with a specially designed column setup, to lower pressure inside the entire column, speeding up analysis.
Detection of Sibutramine in Slimming Products by HPTLC
This application note is suitable for the identification of sibutramine in crude material or finished products in a routine setup.
HILIC Analysis for Polar Modifications of Proteins and Peptides
Learn the advantages of HILIC to measure and monitor glycosylation, deamidation, and oxidation, which are critical for the function and form of proteins and peptides.
Separation of Antiretrovirals
Antiretrovirals have come back to the forefront of separation science at this moment in time, as they have found use in the fight against SARS-CoV-2.